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GHK-Cu

GHK-Cu is a naturally occurring copper-binding peptide composed of three amino acids (glycine, histidine, and lysine). It was first identified in human plasma and is also found in saliva and urine. This peptide is known for its role in tissue remodelling, skin health, and cellular repair processes.

By binding to copper ions, GHK-Cu forms a biologically active complex that has been widely studied for its influence on regeneration, inflammation, and gene expression linked to healing.

Price range: R700,00 through R750,00

Key Benefits

Key Research Areas & Observed Effects

In laboratory and preclinical research, GHK-Cu has been associated with:

Support for skin regeneration and wound healing
Stimulation of collagen and elastin production
Modulation of inflammatory responses
Potential improvement in skin elasticity and firmness in models
Promotion of hair follicle activity in experimental settings
Antioxidant activity and cellular protection
Most of these findings are derived from in vitro and animal studies, with limited large-scale human clinical data available.

How It Works

Mechanism of Action (Research Insights)

GHK-Cu has been shown to interact with multiple biological systems involved in repair and regeneration:

Gene Expression Modulation:
Research suggests it can influence genes associated with tissue repair, inflammation, and antioxidant activity.
Collagen & Extracellular Matrix Support:
It promotes the production of collagen, glycosaminoglycans, and other structural proteins essential for skin and connective tissue integrity.
Copper Transport & Utilisation:
The peptide acts as a carrier for copper ions, which are important for enzymatic processes involved in healing.
Anti-Inflammatory Effects:
GHK-Cu may help regulate inflammatory cytokines, supporting improved recovery environments in experimental models.
Antioxidant Activity:
It has demonstrated the ability to help reduce oxidative stress, which plays a role in ageing and tissue damage.

Research Applications

Scientific Applications

GHK-Cu is widely studied in research focusing on:

Skin ageing and cosmetic science
Wound healing and tissue regeneration
Hair growth and follicle stimulation models
Anti-inflammatory and antioxidant research
Dermatological and extracellular matrix studies
It is frequently explored in both medical and cosmetic research due to its broad biological activity.

Product Information

Summary

GHK-Cu is a well-studied peptide in the field of regenerative and cosmetic research, particularly for its role in skin repair, collagen production, and inflammation control. While early findings are promising, further human research is required to fully establish its safety profile and effectiveness.

Important Disclaimer

GHK-Cu is classified as a research compoundand is not approved for human use by regulatory authorities such as the FDA or SAHPRA.

All information provided is intended strictly for scientific and laboratory research purposes and should not be interpreted as medical advice

 

Protocol Name

Laboratory Handling & Preparation (Research Use Only)

Vial Size

Vial Size: 5 mg lyophilised powder

Reconstitution

Reconstitution Guide:
Add 2 mL of bacteriostatic water to achieve a concentration of approximately 2.5 mg/mL. Allow to dissolve gently—do not shake.

Notes

Measurement Reference:
At 2.5 mg/mL, 0.01 mL (1 unit on a U-100 insulin syringe) equals 25 mcg

Storage

Storage Guidelines:

Unreconstituted: Store frozen for long-term stability
Reconstituted: Refrigerate (2–8 °C) and use within approximately 4 weeks
Protect from light and avoid repeated freeze-thaw cycles